I've been running this recently self-upgraded version of the signet spiker. It works unmatched wonders:
Deadly Arts: 16
Air Magic: 12
Deadly Paradox
Augury of Death
Dancing Daggers
Blinding Surge
Entangling Asp
Signet of Shadows
Signet of Toxic Shock
Enduring Toxin
Always maintain Deadly Paradox. Slap on Augury, then move right down. Dancing Daggers does 78 damage, Surge 55 or so, Asp adds poison. Shadows and Shock deal 206 total. Slap on Enduring Toxic if needed and run out. Your damage is as follows:
78-daggers
55-surge
100-shadows
106-shock
110(ish)-augury
About 450 damage, with degeneration going at a rate of 8 damage per second during the spike, and 18 per second after the fight.
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